Ovid Therapeutics Says Preclinical Data of OV101 Shows Behavioral Improvements in Fragile X Syndrome Model

Ovid Therapeutics Says Preclinical Data of OV101 Shows Behavioral Improvements in Fragile X Syndrome Model

New York-based Ovid Therapeutics (OVID) reported Monday new positive preclinical data on OV101 showing normalization of behavioral abnormalities resembling those seen in people with Fragile X syndrome. “Treatment with OV101 results in significant behavioral improvements that are consistent across all behavioral endpoints tested,” said Matthew During, chief scientific officer. “We designed this study to deepen our understanding of the mechanisms of action and potential benefit of OV101 to treat patients […]

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James River Group Expects $10 Mln Combined Hit From Hurricanes Narvey

James River Group Expects $10 Mln Combined Hit From Hurricanes Narvey

James River Group (JRVR) said on Monday that its initial pretax loss estimate from Hurricanes Harvey, Irma and Maria is expected to be about $10 million, net of reinsurance and reinstatement premiums. This loss estimate is based on its current evaluation of the impacted contracts and are subject to change due to, among other factors, the complexity of the claims and preliminary nature of the information available when it prepared […]

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Asian ADRs Move Higher in Friday Trading

Asian ADRs Move Higher in Friday Trading

American depository receipts of Asian stocks were trading 0.88% higher at 175.57 on the Bank of New York Mellon Asia ADR Index on Friday. In North Asia, the gainers were led by consumer lending company China Rapid Finance (XRF), and semiconductor company Semiconductor Manufacturing International (SMI), which rose 7.8% and 7.2% respectively. They were followed by Baozun (BZUN), a brand e-commerce solutions company, higher 4.8%, and Autohome (ATHM), a website […]

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EP Energy Says Sales Volumes Slightly Impacted by Hurricane Harvey

EP Energy Says Sales Volumes Slightly Impacted by Hurricane Harvey

EP Energy (EPE) said Friday that while its facilities sustained no damage due to hurricane Harvey and drilling operations continued throughout the storm, the company’s sales volumes were down slightly due to temporary losses of downstream infrastructure and markets. The Q3 storm impact to company production volumes was approximately 0.9 thousand barrels of equivalent production per day (MBoe/d), including 0.3 thousand barrels of oil production per day (MBo/d), in the […]

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CRISPR Wins Grant to Research Friedreich’s Ataxia Treatments From Research Alliance

CRISPR Wins Grant to Research Friedreich’s Ataxia Treatments From Research Alliance

CRISPR Therapeutics (CRSP), a genome editing company that seeks to create transformative medicine for serious diseases, said on Friday it received, the Kyle Bryant Translational Research Award, from Friedreich’s Ataxia Research Alliance (FARA), a non-profit organization seeking a cure for Friedreich’s Ataxia (FA). The grant is awarded to fund research on CRISPR/Cas9-based gene-editing approaches to treat FA. The research will be performed in collaboration with Dr. Marek Napierala at the […]

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Ethan Allen Interiors Sees Fiscal Q1 EPS And Revenues Below Analyst Estimates

Ethan Allen Interiors Sees Fiscal Q1 EPS And Revenues Below Analyst Estimates

Ethan Allen Interiors (ETH), a furnishings retailer, said Thursday it expects to report fiscal Q1 adjusted earnings in the range of $0.27 to $0.28 per share, down from $0.43 in Q1 and missing the estimate of $0.45 from analysts polled by Capital IQ. The company expects revenue in the quarter ended Sept. 30 of $181.3 million, down from $193.3 million in the same period a year ago and short of […]

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Wall Street Leans Back Pre-Bell; Futures Red

Wall Street Leans Back Pre-Bell; Futures Red

Wall Street pre-bell Thursday is leaning back, with U.S. stock index futures pointing to an opening off perhaps 0.10% from Wednesday’s close, although the tech-heavy Nasdaq may open evenly. European bourses are mixed though London is up, while Asian exchanges closed solidly higher, led by Seoul which hit fresh all-time highs on the Kospi index. Nafta talks continue. European Central Bank President Mario Draghi is slated for a panel about […]

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AcelRx Shares Plunge 51% Pre-Bell After FDA Says Cannot Approve Dsuvia Application in Present Form

AcelRx Shares Plunge 51% Pre-Bell After FDA Says Cannot Approve Dsuvia Application in Present Form

AcelRx Pharmaceuticals (ACRX) shares were down over 51% in recent pre-market trade after the company said it received a complete response letter (CRL) from the U.S. Food and Drug Administration in which the regulator said it cannot approve the new drug application (NDA) for Dsuvia in its present form. The FDA provided recommendations needed for resubmission, AcelRx said. Dsuvia is a synthetic opioid analgesic indicated for the treatment of patients […]

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Wall Street Steady Pre-Bell

Wall Street Steady Pre-Bell

Wall Street pre-bell Thursday is flatfooted, with U.S. stock index futures pointing to an opening bell largely unchanged from Wednesday’s close, although the Nasdaq may open slightly higher. European bourses are mixed while Asian exchanges were closed on holiday, or muted. Spain-Catalonia relations remain strained, but Spanish stocks have stabilized. Google introduced its new smartphone, named the Pixel 2, and also wireless headphones, dubbed Pixel Buds, touted as able to […]

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General Motors’ Price Target Raised to $44 From $38 by RBC

General Motors’ Price Target Raised to $44 From $38 by RBC

General Motors (GM) received a price-target increase Thursday from RBC Capital Markets to slightly above the stock’s Wednesday closing price as the firm said a 20% rally in the auto maker’s stock since the end of August may have been warranted. The new price target is $44 per share, up from $38. This compares with a Wednesday closing price of $43.78 and a fresh record high hit in Wednesday’s intraday […]

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